從凱文(wén)出發，向世界奔跑

很(hěn)多(duō)家長(cháng)發現

14-16歲左右的孩子是“半成熟”的

既有(yǒu)獨立成熟的一面

又(yòu)突然從懂事的“乖寶寶”

一夜之間變成了叛逆的“調皮鬼”

也就造成了教育階段最困難的時期

但是在朝陽凱文(wén)

這個年齡的孩子卻忙得顧不上淘氣

朝陽凱文(wén)學(xué)校擁有(yǒu)大學(xué)科(kē)研水準的STEM實驗室，能(néng)夠進行活性蛋白質(zhì)的提煉并擁有(yǒu)人T淋巴細胞白血病細胞，在科(kē)創研究中(zhōng)心負責人Edward Gasanoff教授的帶領下，每一屆國(guó)際課程項目（ICP）的中(zhōng)學(xué)生均可(kě)以從7年級開始投身參與科(kē)研項目，直至10年級結束，為(wèi)期四年。

目前，Edward教授帶領10年級學(xué)生，正全力投身于“蜂毒抗癌科(kē)創項目研究”。該項目旨在探索蜂毒分(fēn)餾物(wù)對癌細胞的藥理(lǐ)特性，并尋找可(kě)能(néng)具(jù)有(yǒu)殺傷癌細胞能(néng)力的分(fēn)餾物(wù)，教授和參與的同學(xué)們預計在學(xué)年結束時完成階段性研究，并将其結果發送到歐洲研究機構的實驗室進行進一步研究。

蜂毒項目為(wèi)朝陽凱文(wén)的STEM學(xué)生提供常用(yòng)的大學(xué)水平實驗方法的實踐經驗，涉及生物(wù)化學(xué)、生物(wù)物(wù)理(lǐ)學(xué)、生物(wù)技(jì )術和生物(wù)醫(yī)學(xué)科(kē)學(xué)領域。這可(kě)以幫助學(xué)生完成IBDP科(kē)學(xué)課程的實驗項目，是他(tā)們未來職業生涯中(zhōng)非常重要的技(jì )能(néng)。該項目的另一個目标是在高影響力的科(kē)學(xué)期刊上發表由學(xué)生們共同撰寫的文(wén)章，這将極大地支持他(tā)們競争世界頂級大學(xué)的位置。

小(xiǎo)科(kē)普

STEM是科(kē)學(xué)(Science)，技(jì )術(Technology)，工(gōng)程(Engineering)，數學(xué)(Mathematics)四門學(xué)科(kē)英文(wén)首字母的縮寫。

朝陽凱文(wén)的STEM教育注重學(xué)生的創新(xīn)精(jīng)神和實踐能(néng)力培養，這個抗癌科(kē)研項目為(wèi)學(xué)生們提供了展示和發展這些能(néng)力的寶貴機會。學(xué)生們在項目中(zhōng)面臨挑戰，學(xué)會了如何運用(yòng)學(xué)校所學(xué)的知識和技(jì )能(néng)，探索前沿科(kē)技(jì )領域，并在實踐中(zhōng)提升自己的科(kē)學(xué)素養。

朝陽凱文(wén)學(xué)生聯合署名(míng)國(guó)際論文(wén)列表

Academic Papers

2023年發表

Non-bilayer Lipid Phases Modulate the Structure and Functions of Mitochondrial Membranes: Pharmacological Relevance

《非雙層脂質(zhì)相調節線(xiàn)粒體(tǐ)膜的結構和功能(néng)：藥理(lǐ)學(xué)相關性研究》

刊物(wù)：美國(guó)生物(wù)醫(yī)學(xué)科(kē)學(xué)研究雜志(zhì)

作(zuò)者：Edward Gasanoff、Alice T.、Yaxin H.

2023年發表

Cationic Proteins Rich in Lysine Residue Trigger Formation of Non-bilayer Lipid Phases in Model and Biological Membranes: Biophysical Methods of Study

《富含賴氨酸殘基的陽離子蛋白質(zhì)在人造膜模型和生物(wù)膜中(zhōng)誘發非雙層脂質(zhì)相的形成：生物(wù)物(wù)理(lǐ)學(xué)研究方法》

刊物(wù)：膜生物(wù)學(xué)雜志(zhì)

作(zuò)者：Edward Gasanoff、Julie L.

2021年發表

Bee Venom Melittin Disintegrates the Respiration of Mitochondria in Healthy Cells and Lymphoblasts, and Induces the Formation of Non-Bilayer Structures in Model Inner Mitochondrial Membranes

《蜂毒溶血素在健康細胞和淋巴母細胞中(zhōng)解體(tǐ)線(xiàn)粒體(tǐ)的呼吸，并在模型内線(xiàn)粒體(tǐ)膜中(zhōng)誘導非雙層結構的形成》

刊物(wù)：國(guó)際分(fēn)子科(kē)學(xué)雜志(zhì)

作(zuò)者：Edward Gasanoff、Yipeng L.、Feng L.

2021年發表

Role of Non—Bilayer Structures in Mitochondrial Membranes

《非雙層結構在線(xiàn)粒體(tǐ)膜中(zhōng)的作(zuò)用(yòng)》

刊物(wù)：歐洲膜聯合理(lǐ)論/實驗會議 （EJTEMM）

作(zuò)者：Edward Gasanoff、Y.P.L.

2020年發表

A Field-Directed STEM Education to Advance Research in Endocrine Disruptors, Novel Pharmaceuticals and Artificial Enzymes

《為(wèi)推進内分(fēn)泌幹擾物(wù)、新(xīn)型藥物(wù)和人工(gōng)酶的研究而設計的領域導向的STEM教育》

刊物(wù)：EC藥理(lǐ)學(xué)與毒理(lǐ)學(xué)雜志(zhì)

作(zuò)者：Edward Gasanoff、Difei L.

2020年發表

Interaction of Bee Venom Melittin, a Potential Anti-Cancer Drug, with Phosphatidylcholine Membrane Enriched with Phosphatidylserine

《蜂毒溶血素，一種潛在的抗癌藥物(wù)，與富含磷脂酰絲氨酸的磷脂酰膽堿膜的相互作(zuò)用(yòng)》

刊物(wù)：ECronicon 雜志(zhì)

作(zuò)者：Edward Gasanoff、Jiasheng L.

2019年發表

Short-Chained Alcohols Make Membrane Surfaces Conducive for Melittin Action: Implication for the Physiological Role of Alcohols in Cells

《短鏈醇類使膜表面有(yǒu)利于溶血素的作(zuò)用(yòng)：醇類在細胞中(zhōng)的生理(lǐ)作(zuò)用(yòng)意義》

刊物(wù)：細胞雜志(zhì)

作(zuò)者：Edward Gasanoff、Qin H、Harry W.

2019年發表

Naja mossambica mossambica Cobra Cardiotoxin Targets Mitochondria to Disrupt Mitochondrial Membrane Structure and Function

《莫桑比克眼鏡蛇心髒毒素靶向線(xiàn)粒體(tǐ)以破壞線(xiàn)粒體(tǐ)膜結構和功能(néng)的研究》

刊物(wù)：毒素

作(zuò)者：Edward Gasanoff、Feng L.、Zhengyao C.

科(kē)創項目的成功不僅體(tǐ)現了朝陽凱文(wén)STEM教育的成果，還為(wèi)學(xué)生們的未來學(xué)術和職業發展奠定了堅實的基礎。學(xué)生們的努力和成就将激勵更多(duō)年輕人投身科(kē)學(xué)研究，為(wèi)社會健康和科(kē)技(jì )創新(xīn)做出貢獻。

近期活動預告

歡迎您掃碼預約5月25日9:00 朝陽凱文(wén)開放日 了解課程設置、深度體(tǐ)驗朝陽凱文(wén)藝術、體(tǐ)育、科(kē)創多(duō)元化發展的全人教育，感知好教育的樣子。

CKWA high school students are diving into cancer research projects as part of the innovation and entrepreneurship program

CKWA boasts a university-level STEM lab capable of extracting active proteins and housing human T-lymphocyte leukemia cells. Under the leadership of Professor Edward Gasanoff, head of the Science and Innovation Research Center, every student in the International Curriculum Program (ICP) can participate in research projects starting from 7th grade until the end of 10th grade, spanning four years.

Currently, Professor Edward is leading 10th-grade students in the “Bee Venom Anti-Cancer Innovation Project.” This project aims to explore the pharmacological properties of bee venom fractions on cancer cells and identify fractions that may have cancer cell-killing capabilities. The professor and participating students aim to complete a preliminary study by the end of the academic year and send their results to a European research institution’s laboratory for further analysis.

The bee venom project provides CKWA’s STEM students with hands-on experience using common university-level experimental methods in the fields of biochemistry, biophysics, biotechnology, and biomedical sciences. This experience can help students complete experimental projects for the IBDP science courses, providing them with crucial skills for their future careers. Another goal of the project is to publish an article co-authored by the students in a high-impact scientific journal, significantly enhancing their prospects of securing places at top universities worldwide.

CKWA’s STEM education emphasizes fostering students’ innovative spirit and practical skills. This anti-cancer research project provides a valuable opportunity for students to showcase and develop these abilities. Through the project, students face challenges and learn how to apply the knowledge and skills acquired at school to explore cutting-edge technological fields, thereby enhancing their scientific literacy in practice.

The success of the innovation project not only reflects the achievements of CKWA’s STEM education but also lays a solid foundation for the students’ future academic and career development. The efforts and accomplishments of these students will inspire more young people to engage in scientific research, contributing to societal health and technological innovation.

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